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Pylera - FDA prescribing information, side effects and uses

Publication date: 2018-11-15 23:22

Some Helicobacter -like organisms (HLOs) have been detected by specific polymerase chain reaction tests. The first of these HLOs was described in ferrets and is called Helicobacter mustelae. Helicobacter hepaticus has been described in Syrian hamsters. These HLOs are useful for researching H pylori infection modalities.

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Photosensitivity , manifested by an exaggerated sunburn reaction, has been observed in patients taking tetracycline [see ADVERSE REACTIONS ]. Patients apt to be exposed to direct sunlight or ultraviolet light should be advised that this reaction can occur with tetracycline drugs. Instruct patients taking PYLERA to avoid exposure to the sun or sun lamps. Discontinue treatment at the first evidence of skin erythema.

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8758 Bismuth subcitrate potassium may cause a temporary and harmless darkening of the stool. However, this change does not interfere with standard tests for occult blood.

Each PYLERA capsule contains the following inactive ingredients: Magnesium Stearate NF, Lactose Monohydrate NF, Talc USP, Gelatin USP, and Titanium Dioxide NF, Printed in red ink.

Surgical intervention is not required for patients with H pylori infection, but it may be a consideration for patients with severe complications, such as cancer.

There was evidence of mutagenicity by tetracycline hydrochloride in two in vitro mammalian cell assay systems (L56789y mouse lymphoma and Chinese hamster lung cells).

Alcoholic beverages or other products containing propylene glycol should not be consumed during and for at least 8 days after therapy with PYLERA. A disulfiram-like reaction (abdominal cramps, nausea, vomiting, headaches, and flushing) may occur due to the interaction between alcohol or propylene glycol and metronidazole, a component of PYLERA [see DRUG INTERACTIONS ].

Taking Pylera during pregnancy may affect tooth and bone development in the unborn baby. Taking tetracycline during the last half of pregnancy can cause permanent tooth discoloration later in the baby's life. Tell your doctor if you are pregnant or if you become pregnant while using this medicine.

Clinical Indications for Helicobacter Test INFAI ® Helicobacter Test INFAI ® detects infection of the stomach by the bacterium Helicobacter pylori , the primary causative agent in most cases of peptic ulcer disease. The &sup6 &sup8 C-urea breath test is non-invasive and non-radioactive and has been recommended by the leading societies of gastroenterology ( European Society for Primary Care Gastroenterology European Helicobacter pylori Study Group ) for use both before and after eradication treatment.

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Pylera - FDA prescribing information, side effects and uses Bismuth subcitrate potassium metronidazole tetracycline

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